濠︾鍗冮噾鐗囩⒑瀵︿笉鑳介毃渚垮悆銆傚畠鏄竴绋腑鎴愯棩锛屼富瑕佸姛鏁堟槸娓呯啽鍒╂繒銆佺泭姘ｅ寲鐦€锛岄嚌灏嶆繒鐔遍€犳垚鐨勫付涓嬬梾銆佸瓙瀹収鑶滅値銆佺泦鑵旂値绛夋湁瑾跨悊鏁堟灉銆傜劧鑰岋紝濡傛灉娌掓湁鐩告噳鐨勭櫏鐙€鎴栨湭缍撻啱鐢熸寚灏庯紝鐩茬洰鐢ㄨ棩鍙兘鏈冨紩璧疯儍鑵搁亾涓嶉仼銆侀亷鏁忓弽鎳夌瓑鍟忛銆傚洜姝わ紝鏈夊│绉戠柧鐥呯櫏鐙€鐨勫コ鎬ф噳瑭查€茶鍏ㄩ潰鐨勬鏌ュ悗锛屽湪閱敓鐨勬寚灏庝笅鐢ㄨ棩锛屼互纰轰繚钘ョ墿鐨勬湁鏁堟€у拰瀹夊叏鎬с€�
姝ゅ锛屽瓡濠︾鐢ㄥ│绉戝崈閲戠墖锛屼笖灏戝コ銆佺禃缍撳悗鎮ｈ€呬互鍙婃湁楂樿澹撱€佸績鑷熺梾銆佽倽鐥呫€佺硸灏跨梾銆佽厧鐥呯瓑鎱㈡€х梾鍤撮噸鑰呴兘鎳夊湪閱斧鎸囧皫涓嬫湇鐢ㄣ€傚鏋滄湇钘�2鍛ㄧ櫏鐙€鐒＄珐瑙ｏ紝鎳夊強鏅傚幓閱櫌灏辫ê銆�
绺戒箣锛屽│绉戝崈閲戠墖涓嶈兘闅ㄤ究鍚冿紝蹇呴爤鍦ㄩ啱鐢熺殑鎸囧皫涓嬩娇鐢紝浠ュ厤鍑虹従涓嶈壇鍙嶆噳銆�
瀹滆垐甯傚ぇ娴﹁鐢熼櫌
瀹滆垐甯傚嫉婢よ鐢熼櫌
瀹滆垐甯傛箹鐖惰鐢熼櫌
瀹滆垐甯備紡鏉辫鐢熼櫌
涓湅浜烘皯姝﹁璀﹀療8690閮ㄩ殜閱櫌
瀹滆垐甯傚焙浜鐢熼櫌
瀹滆垐甯傛柊鑺宠鐢熼櫌
瀹滆垐甯傚崡鏂拌鐢熼櫌
瀹滆垐甯傝タ娓氳鐢熼櫌
瀹滆垐甯傝惉鐭宠鐢熼櫌
瀹滆垐甯傚崡婕曡鐢熼櫌
瀹滆垐甯傝睈缇╄鐢熼櫌
瀹滆垐甯傝寖閬撹鐢熼櫌
瀹滆垐甯傝姵姗嬭鐢熼櫌
瀹滆垐甯傛壎棰ㄨ鐢熼櫌
瀹滆垐甯傚ぇ濉嶈鐢熼櫌
铇囧窞甯傚惓涓崁瑗垮北閹伐杈叉⿱绀惧崁琛涚敓鏈嶅嫏绔�
瀹滆垐甯傚垎姘磋鐢熼櫌
瀹滆垐甯傛柊鑾婅鐢熼櫌
瀹滆垐甯傝寳宥鸿鐢熼櫌
瀹滆垐甯傚杽鍗疯鐢熼櫌
瀹滆垐甯傛柊琛楄鐢熼櫌
瀹滆垐甯傛寰戣鐢熼櫌
瀹滆垐甯傚緪鑸嶉啱闄�
瀹滆垐甯傞濉樿鐢熼櫌
瀹滆垐甯傛綐瀹跺）琛涚敓闄�
瀹滆垐甯傚煗闋鐢熼櫌
瀹滆垐甯傝姵鑾婅鐢熼櫌
瀹滆垐甯傞兊鍫傝鐢熼櫌
瀹滆垐甯傚疁璞愯鐢熼櫌
閬╃敤浜庝績閫插眬閮ㄨ娑插惊鐠般€佽紨鍔╂秷鐐庛€佹秷鑵拰姝㈢棝銆傞仼鐢ㄤ簬灏嶉牳妞庣梾銆佽偐鍛ㄧ値銆侀璩鐢熴€佽叞妞庨枔鐩ょ獊鍑恒€侀棞绡€鐐庛€佽倢绾栫董鐐庛€佽粺绲勭箶鎵尗鍌枫€佹€ユ€ц叞鑲屽嫗鎼嶇殑杓斿姪娌荤檪銆傞仼鐢ㄤ簬绶╄В鑵块儴闂滅瘈銆佽倢鑲夌柤鐥涘強鑲遍澶栦笂楂佺値寮曡捣鐨勯棞绡€婊戣啘鐐庢墍鑷翠箣鐤肩棝銆�
閹挸锛岀鐥帮紝骞冲枠锛屾秷鐐庛€傜敤浜庡挸鍠樺強鎱㈡€ф敮姘ｇ鐐庡挸鍡姐€�
1.鍘熺櫦鎬ч珮鑶藉浐閱囪鐧ユ湰鍝佷綔鐐洪２椋熸帶鍒朵互澶栫殑杓斿姪娌荤檪,鍙柈鐛ㄦ垨鑸嘓MG-CoA閭勫師閰舵姂鍒�(浠栨眬椤�)鑱悎鎳夌敤浜庢不鐧傚師鐧兼€�(闆滃悎瀛愬鏃忔€ф垨闈炲鏃忔€�)楂樿喗鍥洪唶琛€鐧ワ紝鍙檷浣庣附鑶藉浐閱�(TC)銆佷綆瀵嗗害鑴傝泲鐧借喗鍥洪唶(LDL-C)銆佽級鑴傝泲鐧紹(ApoB)銆� 2.绱斿悎瀛愬鏃忔€ч珮鑶藉浐閱囪鐧�(HoFH)鏈搧鑸囦粬姹€椤炶伅鍚堟噳鐢紝鍙綔鐐哄叾浠栭檷鑴傛不鐧傜殑杓斿姪鐧傛硶(濡侺DL-C琛€婕垮垎闆㈢疆鎻涙硶)锛屾垨鍦ㄥ叾浠栭檷鑴傛不鐧傜劇鏁堟檪鐢ㄤ簬闄嶄綆HoFH鎮ｈ€呯殑TC鍜孡DL-C姘村钩銆� 3.绱斿悎瀛愯胺鐢鹃唶琛€鐧�(鎴栨鐗╃斁閱囪鐧�)鏈搧浣滅偤椋查鎺у埗浠ュ鐨勮紨鍔╂不鐧傦紝鐢ㄤ簬闄嶄綆绱斿悎瀛愬鏃忔€ц胺鐢鹃唶琛€鐧ユ偅鑰呯殑璋风斁閱囧拰妞嶇墿鐢鹃唶姘村钩銆�
瑗垮湴閭ｉ潪閬╃敤浜庢不鐧傚媰璧峰姛鑳介殰绀欍€�
1.瀛ｇ瘈鎬ч亷鏁忔€ч蓟鐐庨仼鐢ㄤ簬绶╄В鎴愪汉鍜�6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑瀛ｇ瘈鎬ч亷鏁忔€ч蓟鐐庣浉闂滅殑鐧ョ媭锛屽鎵撳櫞鍤忥紝娴侀蓟娑曪紝榧汇€佽叚銆佸枆閮ㄧ櫦鐧€€佺溂鐫涚櫦鐧€€佹疆婵曘€佺櫦绱呫€� 2.鎱㈡€х壒鐧兼€ц晛楹荤柟閬╃敤浜庢不鐧傛垚浜哄拰6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑鎱㈡€х壒鐧兼€ц晛楹荤柟鐨勭毊鑶氱櫏鐙€锛岃兘澶犻’钁楁笡杓曠槞鐧㈠拰棰ㄥ湗鐨勬暩閲忋€�
寤ｆ澅缇呮诞灞卞湅钘ヨ偂浠芥湁闄愬叕鍙告槸涓€瀹跺緸浜嬭棩鍝佺敓鐢�,钘ュ搧缍撶嚐,涓崏钘ユ敹璩肩瓑妤嫏鐨勫叕鍙革紝鎴愮珛浜�2008骞�12鏈�24鏃ワ紝鍏徃鍧愯惤鍦ㄥ唬鏉辩渷锛岃┏绱板湴鍧€鐐猴細鎯犲窞甯傚崥缇呯福闀峰閹唬姹曞叕璺倞宥烘帓宸ユキ鍗€锛堢緟娴北钘ユキ鍩庯級;缍撳湅
鍖椾含闊撶編钘ュ搧鏈夐檺鍏徃(浠ヤ笅绨＄ū鍖椾含闊撶編)鎴愮珛浜�1996骞�3鏈堬紝鍏徃鐢㈠搧妤嫏娑夊強鍏掔鐢㈠搧銆佹秷鍖栫鐢㈠搧銆侀绉戠敘鍝併€佹姉鎰熸煋钘ョ瓑闋樺煙锛�98%鐨勭敘鍝佸湪鍦嬪収鎴愮敘锛屼富瑕佺敘鍝佹湁濯藉挭鎰涖€佹槗鍧﹂潨銆佹槗瀹夊钩銆佺編甯稿畨銆佸埄鍕曘€�
銆€銆€鐩婃櫘鐢熼泦鍦樹綔鐐轰竴瀹舵湁钁楀叓鍗佸骞村埗钘ョ稉椹楃殑姝愭床鍒惰棩闆嗗湗锛屾搧鏈�20浣欑ó涓婂競鐢㈠搧鍙婇亶甯冨叏鐞冭繎4000鍚嶇殑鍝″伐銆傚叕鍙哥殑鐧煎睍鎴扮暐鏄互涓夊ぇ娌荤檪闋樺煙鍏х殑楂樼鎶€鐢㈠搧鐐哄熀绀庯紝鍗宠叓鐦ゃ€佸収鍒嗘硨銆佺缍撹倢鑲夐鐤剧梾锛岄€欎簺楂�
鍖椾含鍚屼粊鍫傝偂浠芥湁闄愬叕鍙稿悓浠佸爞鍒惰棩寤犳垚绔嬩簬1990骞�11鏈�21鏃ワ紝娉ㄥ唺鍦颁綅浜庡寳浜競澶ц垐鍗€涓棞鏉戠鎶€鍦掑崁澶ц垐鐢熺墿閱棩鐢㈡キ鍩哄湴澶╄泊澶ц33铏燂紝娉曞畾浠ｈ〃浜虹偤寮垫湞鑿€傜稉鐕熻寖鍦嶅寘鎷姞宸ャ€佸埗閫犱腑鎴愯棩锛涘嚭绉熻睛鍏敤鎴�
杓濈憺鍦ㄤ腑鍦嬫キ鍕欒钃嬪叏鍦�300浣欏€嬪煄甯傦紝骞跺湪鑿笂甯備簡浜斿ぇ闋樺煙鐨勯珮鍝佽唱鐨勫壍鏂拌棩鐗╋紝鍖呮嫭鑵槫銆佺柅鑻椼€佹姉鎰熸煋銆佺値鐧ヨ垏鍏嶇柅銆佺綍瑕嬬梾绛夊鍊嬮牁鍩熺殑铏曟柟钘ュ拰鐤嫍銆傚骞翠締锛岃紳鐟炲绲傝嚧鍔涗簬鈥滄垚鐐轰腑鍦嬮啱鐧傝鐢熼珨绯婚噸瑕佺祫鎴�
