甯曢噾妫梾鏃╂湡涓夊ぇ鐧ョ媭鑲屽嫉鍔涢珮銆侀潨姝㈤渿椤拰閬嬪嫊闅滅锛涙澶栬獚鐭ラ殰绀欍€佽鎲跺姏鏀硅畩銆佹鐗╃缍撶梾璁娿€傚笗閲戞．鏃╂湡鏈夐潪閬嬪嫊鐨勭櫏鐙€锛屽寘鎷獚鐭ョ殑闅滅锛岃鎲跺姏鐨勬敼璁婏紝妞嶇墿绁炵稉绯荤当鐥呰畩銆傞偅涔堥亱鍕曠郴绲辩殑涓夊ぇ鐧ョ媭灏辨槸锛氳倢寮靛姏楂樸€侀潨姝㈢殑闇囬～鍜岄亱鍕曢殰绀欓€欎笁鍊嬫柟闈㈢殑琛ㄧ従銆傝倢寮靛姏楂樹娇甯曢噾妫嚭鐝鹃潰鍏疯噳锛岃倢寮靛姏楂樺彲浠ユ湁闂滅瘈銆佽偄楂旀椿鍕曟檪鐨勬姌鍒€鎬х殑鏀硅畩銆佺櫦鍍电殑濮垮嫝锛涢渿椤彲浠ュ緸鍠伌鐨勪竴鏍规墜鎸囥€佽叧瓒鹃枊濮嬶紝閫茶€屽奖闊垮埌鏁村€嬬殑鑲㈤珨锛屾渶鍚庡洓鑲㈤兘鍙互鍑虹従闇囬～锛涢亱鍕曢殰绀欏彲浠ュ嚭鐝炬厡寮电殑姝ユ厠锛岃韩楂斿墠娌栥€佸皬纰庢绛夌瓑锛岄€欏氨鏄畠鐨勪笁澶х櫏鐙€銆�
鑽婂窞濠︾閱櫌
榛冪煶濠︾閱櫌
闅ㄥ窞濠︾閱櫌
閯傚窞濠︾閱櫌
榛冨病濠︾閱櫌
鑽婇杸鐢风閱櫌
鍜稿鐢风閱櫌
瑗勬▕鐢风閱櫌
鑽婂窞鐢风閱櫌
閯傚窞鐢风閱櫌
瀛濇劅鐢风閱櫌
榛冨病鐢风閱櫌
鍗佸牥鐢风閱櫌
瑗勯櫧甯傜敺绉戦啱闄�
璨撮櫧鑵︾櫜閱櫌
榛旇タ鍗楀窞鐤剧梾闋愰槻鎺у埗涓績
娓呴幃甯傚│骞间繚鍋ラ櫌
姝ｅ畨绺ｅ│骞间繚鍋ラ櫌
娌挎渤鍦熷鏃忚嚜娌荤福濠﹀辜淇濆仴闄�
榛斿崡宸炵簿绁炵梾閱櫌
绻旈噾绺ｅ│骞间繚鍋ラ櫌
璨村窞鐪佽伔宸ラ啱闄�
瑗垮畨甯傚彛鑵旈啱闄�
閵呭窛甯傞儕鍗€涓啱闄�
瑗垮畨娉屽翱鐥呴啱闄�
闄滆タ鐪佸湴鏂圭梾闃叉不鐮旂┒鎵€
瀵堕洖绺ｅ崈娌抽绉戦啱闄�
瀵堕洖甯傛腑婵卞崁濠﹀辜淇濆仴绔�
鍜搁櫧甯傛腑鍩庡崁鍙ｈ厰閱櫌
鍜搁櫧甯傜Е閮藉崁涓啱闄�
閬╃敤浜庝績閫插眬閮ㄨ娑插惊鐠般€佽紨鍔╂秷鐐庛€佹秷鑵拰姝㈢棝銆傞仼鐢ㄤ簬灏嶉牳妞庣梾銆佽偐鍛ㄧ値銆侀璩鐢熴€佽叞妞庨枔鐩ょ獊鍑恒€侀棞绡€鐐庛€佽倢绾栫董鐐庛€佽粺绲勭箶鎵尗鍌枫€佹€ユ€ц叞鑲屽嫗鎼嶇殑杓斿姪娌荤檪銆傞仼鐢ㄤ簬绶╄В鑵块儴闂滅瘈銆佽倢鑲夌柤鐥涘強鑲遍澶栦笂楂佺値寮曡捣鐨勯棞绡€婊戣啘鐐庢墍鑷翠箣鐤肩棝銆�
閹挸锛岀鐥帮紝骞冲枠锛屾秷鐐庛€傜敤浜庡挸鍠樺強鎱㈡€ф敮姘ｇ鐐庡挸鍡姐€�
1.鍘熺櫦鎬ч珮鑶藉浐閱囪鐧ユ湰鍝佷綔鐐洪２椋熸帶鍒朵互澶栫殑杓斿姪娌荤檪,鍙柈鐛ㄦ垨鑸嘓MG-CoA閭勫師閰舵姂鍒�(浠栨眬椤�)鑱悎鎳夌敤浜庢不鐧傚師鐧兼€�(闆滃悎瀛愬鏃忔€ф垨闈炲鏃忔€�)楂樿喗鍥洪唶琛€鐧ワ紝鍙檷浣庣附鑶藉浐閱�(TC)銆佷綆瀵嗗害鑴傝泲鐧借喗鍥洪唶(LDL-C)銆佽級鑴傝泲鐧紹(ApoB)銆� 2.绱斿悎瀛愬鏃忔€ч珮鑶藉浐閱囪鐧�(HoFH)鏈搧鑸囦粬姹€椤炶伅鍚堟噳鐢紝鍙綔鐐哄叾浠栭檷鑴傛不鐧傜殑杓斿姪鐧傛硶(濡侺DL-C琛€婕垮垎闆㈢疆鎻涙硶)锛屾垨鍦ㄥ叾浠栭檷鑴傛不鐧傜劇鏁堟檪鐢ㄤ簬闄嶄綆HoFH鎮ｈ€呯殑TC鍜孡DL-C姘村钩銆� 3.绱斿悎瀛愯胺鐢鹃唶琛€鐧�(鎴栨鐗╃斁閱囪鐧�)鏈搧浣滅偤椋查鎺у埗浠ュ鐨勮紨鍔╂不鐧傦紝鐢ㄤ簬闄嶄綆绱斿悎瀛愬鏃忔€ц胺鐢鹃唶琛€鐧ユ偅鑰呯殑璋风斁閱囧拰妞嶇墿鐢鹃唶姘村钩銆�
瑗垮湴閭ｉ潪閬╃敤浜庢不鐧傚媰璧峰姛鑳介殰绀欍€�
1.瀛ｇ瘈鎬ч亷鏁忔€ч蓟鐐庨仼鐢ㄤ簬绶╄В鎴愪汉鍜�6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑瀛ｇ瘈鎬ч亷鏁忔€ч蓟鐐庣浉闂滅殑鐧ョ媭锛屽鎵撳櫞鍤忥紝娴侀蓟娑曪紝榧汇€佽叚銆佸枆閮ㄧ櫦鐧€€佺溂鐫涚櫦鐧€€佹疆婵曘€佺櫦绱呫€� 2.鎱㈡€х壒鐧兼€ц晛楹荤柟閬╃敤浜庢不鐧傛垚浜哄拰6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑鎱㈡€х壒鐧兼€ц晛楹荤柟鐨勭毊鑶氱櫏鐙€锛岃兘澶犻’钁楁笡杓曠槞鐧㈠拰棰ㄥ湗鐨勬暩閲忋€�
寤ｆ澅缇呮诞灞卞湅钘ヨ偂浠芥湁闄愬叕鍙告槸涓€瀹跺緸浜嬭棩鍝佺敓鐢�,钘ュ搧缍撶嚐,涓崏钘ユ敹璩肩瓑妤嫏鐨勫叕鍙革紝鎴愮珛浜�2008骞�12鏈�24鏃ワ紝鍏徃鍧愯惤鍦ㄥ唬鏉辩渷锛岃┏绱板湴鍧€鐐猴細鎯犲窞甯傚崥缇呯福闀峰閹唬姹曞叕璺倞宥烘帓宸ユキ鍗€锛堢緟娴北钘ユキ鍩庯級;缍撳湅
鍖椾含闊撶編钘ュ搧鏈夐檺鍏徃(浠ヤ笅绨＄ū鍖椾含闊撶編)鎴愮珛浜�1996骞�3鏈堬紝鍏徃鐢㈠搧妤嫏娑夊強鍏掔鐢㈠搧銆佹秷鍖栫鐢㈠搧銆侀绉戠敘鍝併€佹姉鎰熸煋钘ョ瓑闋樺煙锛�98%鐨勭敘鍝佸湪鍦嬪収鎴愮敘锛屼富瑕佺敘鍝佹湁濯藉挭鎰涖€佹槗鍧﹂潨銆佹槗瀹夊钩銆佺編甯稿畨銆佸埄鍕曘€�
銆€銆€鐩婃櫘鐢熼泦鍦樹綔鐐轰竴瀹舵湁钁楀叓鍗佸骞村埗钘ョ稉椹楃殑姝愭床鍒惰棩闆嗗湗锛屾搧鏈�20浣欑ó涓婂競鐢㈠搧鍙婇亶甯冨叏鐞冭繎4000鍚嶇殑鍝″伐銆傚叕鍙哥殑鐧煎睍鎴扮暐鏄互涓夊ぇ娌荤檪闋樺煙鍏х殑楂樼鎶€鐢㈠搧鐐哄熀绀庯紝鍗宠叓鐦ゃ€佸収鍒嗘硨銆佺缍撹倢鑲夐鐤剧梾锛岄€欎簺楂�
鍖椾含鍚屼粊鍫傝偂浠芥湁闄愬叕鍙稿悓浠佸爞鍒惰棩寤犳垚绔嬩簬1990骞�11鏈�21鏃ワ紝娉ㄥ唺鍦颁綅浜庡寳浜競澶ц垐鍗€涓棞鏉戠鎶€鍦掑崁澶ц垐鐢熺墿閱棩鐢㈡キ鍩哄湴澶╄泊澶ц33铏燂紝娉曞畾浠ｈ〃浜虹偤寮垫湞鑿€傜稉鐕熻寖鍦嶅寘鎷姞宸ャ€佸埗閫犱腑鎴愯棩锛涘嚭绉熻睛鍏敤鎴�
杓濈憺鍦ㄤ腑鍦嬫キ鍕欒钃嬪叏鍦�300浣欏€嬪煄甯傦紝骞跺湪鑿笂甯備簡浜斿ぇ闋樺煙鐨勯珮鍝佽唱鐨勫壍鏂拌棩鐗╋紝鍖呮嫭鑵槫銆佺柅鑻椼€佹姉鎰熸煋銆佺値鐧ヨ垏鍏嶇柅銆佺綍瑕嬬梾绛夊鍊嬮牁鍩熺殑铏曟柟钘ュ拰鐤嫍銆傚骞翠締锛岃紳鐟炲绲傝嚧鍔涗簬鈥滄垚鐐轰腑鍦嬮啱鐧傝鐢熼珨绯婚噸瑕佺祫鎴�
