閬�(y霉n)鍕曞悗涔虫埧鑴圭棝鎬庝箞杈�
閬�(y霉n)鍕曞悗涔虫埧鑴圭棝鎬庝箞杈�
鐥呮儏鎻忚堪锛�
閱�(y墨)鐢熷洖绛旓細
閬�(y霉n)鍕曞悗涔虫埧鑴圭棝锛屽彲浠ヤ娇鐢ㄧ啽鏁风殑鏂瑰紡绶╄В銆傚洜?y脿n)妯佃岸\(y霉n)鍕曢亷绋嬩腑鏈夊彲鑳芥媺鍌蜂钩鎴挎繁闈㈣兏鑲岋紝寰炶€屽紩璧风柤鐥涳紝浣跨敤鐔辨暦鍙互绶╄В鐤肩棝鎰燂紱濡傛灉鐤肩棝鐨勬寔绾�(x霉)鏅�(sh铆)闁撹純闀凤紝鍓囬渶瑕佸幓閱�(y墨)闄㈠仛涔虫埧妾㈡煡锛屾帓鏌ユ槸鍚﹀瓨鍦ㄤ钩鎴跨梾璁娿€傚湪閬�(y霉n)鍕曟檪(sh铆)涔熼渶瑕佺洝閲忎僵鎴撮亱(y霉n)鍕曡兏缃╋紝閫欐ǎ鍙互娓涘皯涔虫埧鐨勯绨搞€�
鐩搁棞(gu膩n)鎺ㄨ枽
-
澶悍绺ｈ鏍撶梾閱�(y墨)闄�
-
澶悍绺ｅ叕璨�(f猫i)閱�(y墨)鐧傞啱(y墨)闄�
-
楣块倯绺ｅ叕鐧傞啱(y墨)闄�
-
姹濆崡绺ｅ叕璨�(f猫i)閱�(y墨)鐧傞啱(y墨)闄�
-
鏂拌敗绺ｇ浜屼汉姘戦啱(y墨)闄�
-
娌堜笜绺ｅ叕璨�(f猫i)閱�(y墨)鐧傞啱(y墨)闄�
-
姝ｉ櫧绺ｅ叕璨�(f猫i)閱�(y墨)鐧傞啱(y墨)闄�
-
闁嬪皝鑵庣梾閱�(y墨)闄�
-
槎村鐗涚毊鐧啱(y墨)闄�
-
鐒︿綔鐗涚毊鐧啱(y墨)闄�
-
淇￠櫧鑵槫閱�(y墨)闄�
-
骞抽爞灞辩墰鐨櫖閱�(y墨)闄�
-
淇￠櫧鐗涚毊鐧啱(y墨)闄�
-
鍗楅櫧鐗涚毊鐧啱(y墨)闄�
-
婕渤鐗涚毊鐧啱(y墨)闄�
-
涓夐杸宄界墰鐨櫖閱�(y墨)闄�
-
婵櫧鐗涚毊鐧啱(y墨)闄�
-
瑷辨槍鐗涚毊鐧啱(y墨)闄�
-
瀹夐櫧鐗涚毊鐧啱(y墨)闄�
-
鏂伴剦(xi膩ng)鐗涚毊鐧啱(y墨)闄�
-
鍟嗕笜鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
鍛ㄥ彛鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
椐愰Μ搴楃櫧鐧滈ⅷ(f膿ng)閱�(y墨)闄�
-
瑷辨槍鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
婕渤鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
涓夐杸宄界櫧鐧滈ⅷ(f膿ng)閱�(y墨)闄�
-
鐒︿綔鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
槎村鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
瀹夐櫧鐧界櫆棰�(f膿ng)閱�(y墨)闄�
-
鏂伴剦(xi膩ng)鐧界櫆棰�(f膿ng)閱�(y墨)闄�
鎺ㄨ枽鏂囩珷
鎺ㄨ枽鍟忕瓟
甯歌钘ュ搧
-
钘�閬�(yu菐n)绱呭娑堢値姝㈢棝璨�
閬╃敤浜庝績閫�(j矛n)灞€閮ㄨ娑插惊鐠�(hu谩n)銆佽紨鍔╂秷鐐庛€佹秷鑵拰姝㈢棝銆傞仼鐢ㄤ簬灏嶉牳妞庣梾銆佽偐鍛ㄧ値銆侀璩�(zh矛)澧炵敓銆佽叞妞庨枔鐩ょ獊鍑恒€侀棞(gu膩n)绡€(ji茅)鐐庛€佽倢绾栫董鐐庛€佽粺绲勭箶鎵尗鍌枫€佹€ユ€ц叞鑲屽嫗鎼嶇殑杓斿姪娌荤檪銆傞仼鐢ㄤ簬绶╄В鑵块儴闂�(gu膩n)绡€(ji茅)銆佽倢鑲夌柤鐥涘強鑲遍澶栦笂楂佺値寮曡捣鐨勯棞(gu膩n)绡€(ji茅)婊戣啘鐐庢墍鑷翠箣鐤肩棝銆�
-
钘�鍜崇壒闈堣啝鍥�
閹�(zh猫n)鍜筹紝绁涚棸锛屽钩鍠橈紝娑堢値銆傜敤浜庡挸鍠樺強鎱㈡€ф敮姘ｇ鐐庡挸鍡姐€�
-
钘�渚濇姌楹ュ竷鐗�
1.鍘熺櫦(f膩)鎬ч珮鑶藉浐閱囪鐧ユ湰鍝佷綔鐐洪２椋熸帶鍒朵互澶栫殑杓斿姪娌荤檪,鍙柈鐛�(d煤)鎴栬垏HMG-CoA閭勫師閰舵姂鍒�(浠栨眬椤�)鑱�(li谩n)鍚堟噳(y墨ng)鐢ㄤ簬娌荤檪鍘熺櫦(f膩)鎬�(闆滃悎瀛愬鏃忔€ф垨闈炲鏃忔€�)楂樿喗鍥洪唶琛€鐧ワ紝鍙檷浣庣附鑶藉浐閱�(TC)銆佷綆瀵嗗害鑴傝泲鐧借喗鍥洪唶(LDL-C)銆佽級鑴傝泲鐧紹(ApoB)銆� 2.绱斿悎瀛愬鏃忔€ч珮鑶藉浐閱囪鐧�(HoFH)鏈搧鑸囦粬姹€椤炶伅(li谩n)鍚堟噳(y墨ng)鐢紝鍙綔鐐哄叾浠栭檷鑴傛不鐧傜殑杓斿姪鐧傛硶(濡侺DL-C琛€婕垮垎闆㈢疆鎻涙硶)锛屾垨鍦ㄥ叾浠栭檷鑴傛不鐧傜劇鏁堟檪(sh铆)鐢ㄤ簬闄嶄綆HoFH鎮ｈ€呯殑TC鍜孡DL-C姘村钩銆� 3.绱斿悎瀛愯胺鐢鹃唶琛€鐧�(鎴栨鐗╃斁閱囪鐧�)鏈搧浣滅偤椋查鎺у埗浠ュ鐨勮紨鍔╂不鐧傦紝鐢ㄤ簬闄嶄綆绱斿悎瀛愬鏃忔€ц胺鐢鹃唶琛€鐧ユ偅鑰呯殑璋风斁閱囧拰妞嶇墿鐢鹃唶姘村钩銆�
-
钘�鏋告珵閰歌タ鍦伴偅闈炵墖
瑗垮湴閭ｉ潪閬╃敤浜庢不鐧傚媰璧峰姛鑳介殰绀欍€�
-
钘�楣介吀闈炵储闈為偅瀹氱墖
1.瀛ｇ瘈(ji茅)鎬ч亷鏁忔€ч蓟鐐庨仼鐢ㄤ簬绶╄В鎴愪汉鍜�6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑瀛ｇ瘈(ji茅)鎬ч亷鏁忔€ч蓟鐐庣浉闂�(gu膩n)鐨勭櫏鐙€锛屽鎵撳櫞鍤忥紝娴侀蓟娑曪紝榧汇€佽叚銆佸枆閮ㄧ櫦(f膩)鐧€€佺溂鐫涚櫦(f膩)鐧€€佹疆婵曘€佺櫦(f膩)绱呫€� 2.鎱㈡€х壒鐧�(f膩)鎬ц晛楹荤柟閬╃敤浜庢不鐧傛垚浜哄拰6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑鎱㈡€х壒鐧�(f膩)鎬ц晛楹荤柟鐨勭毊鑶氱櫏鐙€锛岃兘澶犻’钁楁笡杓曠槞鐧㈠拰棰�(f膿ng)鍦�(tu谩n)鐨勬暩(sh霉)閲忋€�
钘ヤ紒鍒楄〃
-
浼�寤ｆ澅缇呮诞灞卞湅钘ヨ偂浠芥湁闄愬叕鍙�
寤ｆ澅缇呮诞灞卞湅钘ヨ偂浠芥湁闄愬叕鍙告槸涓€瀹跺緸浜嬭棩鍝佺敓鐢�(ch菐n),钘ュ搧缍�(j墨ng)鐕�,涓崏钘ユ敹璩肩瓑妤�(y猫)鍕�(w霉)鐨勫叕鍙革紝鎴愮珛浜�2008骞�12鏈�24鏃ワ紝鍏徃鍧愯惤鍦ㄥ唬鏉辩渷锛岃┏绱�(x矛)鍦板潃鐐猴細鎯犲窞甯傚崥缇呯福闀峰閹�(zh猫n)寤ｆ睍鍏矾閭婂逗鎺掑伐妤�(y猫)鍗€(q奴)锛堢緟娴北钘ユキ(y猫)鍩庯級;缍�(j墨ng)鍦�
-
浼�鍖椾含闊撶編钘ュ搧鏈夐檺鍏徃
鍖椾含闊撶編钘ュ搧鏈夐檺鍏徃(浠ヤ笅绨＄ū鍖椾含闊撶編)鎴愮珛浜�1996骞�3鏈堬紝鍏徃鐢�(ch菐n)鍝佹キ(y猫)鍕�(w霉)娑夊強鍏掔鐢�(ch菐n)鍝併€佹秷鍖栫鐢�(ch菐n)鍝併€侀绉戠敘(ch菐n)鍝併€佹姉鎰熸煋钘ョ瓑闋�(l菒ng)鍩燂紝98%鐨勭敘(ch菐n)鍝佸湪鍦嬪収(n猫i)鎴愮敘(ch菐n)锛屼富瑕佺敘(ch菐n)鍝佹湁濯藉挭鎰涖€佹槗鍧﹂潨銆佹槗瀹夊钩銆佺編甯稿畨銆佸埄鍕曘€�
-
浼�鍗氱-鐩婃櫘鐢�(澶╂触)鍒惰棩鏈夐檺鍏徃
銆€銆€鐩婃櫘鐢熼泦鍦�(tu谩n)浣滅偤涓€瀹舵湁钁楀叓鍗佸骞村埗钘ョ稉(j墨ng)椹�(y脿n)鐨勬瓙娲插埗钘ラ泦鍦�(tu谩n)锛屾搧鏈�20浣欑ó涓婂競鐢�(ch菐n)鍝佸強閬嶅竷鍏ㄧ悆杩�4000鍚嶇殑鍝″伐銆傚叕鍙哥殑鐧�(f膩)灞曟埌(zh脿n)鐣ユ槸浠ヤ笁澶ф不鐧傞牁(l菒ng)鍩熷収(n猫i)鐨勯珮绉戞妧鐢�(ch菐n)鍝佺偤鍩虹(ch菙)锛屽嵆鑵槫銆佸収(n猫i)鍒嗘硨銆佺缍�(j墨ng)鑲岃倝椤炵柧鐥咃紝閫欎簺楂�
-
浼�鍖椾含鍚屼粊鍫傝偂浠芥湁闄愬叕鍙稿悓浠佸爞鍒惰棩寤�
鍖椾含鍚屼粊鍫傝偂浠芥湁闄愬叕鍙稿悓浠佸爞鍒惰棩寤犳垚绔嬩簬1990骞�11鏈�21鏃ワ紝娉ㄥ唺鍦颁綅浜庡寳浜競澶ц垐鍗€(q奴)涓棞(gu膩n)鏉戠鎶€鍦掑崁(q奴)澶ц垐鐢熺墿閱�(y墨)钘ョ敘(ch菐n)妤�(y猫)鍩哄湴澶╄泊澶ц33铏燂紝娉曞畾浠ｈ〃浜虹偤寮垫湞鑿€傜稉(j墨ng)鐕熻寖鍦嶅寘鎷姞宸ャ€佸埗閫犱腑鎴愯棩锛涘嚭绉熻睛鍏敤鎴�
-
浼�杓濈憺鍒惰棩鏈夐檺鍏徃
杓濈憺鍦ㄤ腑鍦嬫キ(y猫)鍕�(w霉)瑕嗚搵鍏ㄥ湅300浣欏€嬪煄甯傦紝骞跺湪鑿笂甯備簡浜斿ぇ闋�(l菒ng)鍩熺殑楂樺搧璩�(zh矛)鐨勫壍(chu脿ng)鏂拌棩鐗╋紝鍖呮嫭鑵槫銆佺柅鑻椼€佹姉鎰熸煋銆佺値鐧ヨ垏鍏嶇柅銆佺綍瑕嬬梾绛夊鍊嬮牁(l菒ng)鍩熺殑铏曟柟钘ュ拰鐤嫍銆傚骞翠締锛岃紳鐟炲绲傝嚧鍔涗簬鈥滄垚鐐轰腑鍦嬮啱(y墨)鐧傝(w猫i)鐢熼珨绯婚噸瑕佺祫鎴�